L-Triiodothyronine(T3)
Alias:3,3',5-Triiodo-L-thyroninesodiumsalt,Sodium(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate
Purity : 99%
CAS Registry Number: 55-06-1
Einecs No: 200-223-5
MF: C15H11I3NNaO4
MW: 672.96
MS:
Appearance: white or light yellow powder, almost tasteless.
Grade : Pharmaceutical Grade
Storage: Shading, confined preservation
Usage : It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate, such as, treatment of depressive disorders and use as a fat loss supplement
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Sodium L-Triiodothyronine also known as T3,it is a thyroid hormone which affects almost body physiological process.T3 contains three atoms of iodine and is formed by the coupling of one molecule of DIT with one molecule of monoiodotyrosine.Production of T3 and its prohormone thyroxine is activated by thyroid-stimulating hormone.As concentrations of decrease, the anterior pituitary gland increases TSH production of and control system stabilizes the amount of thyroid hormones that are in the bloodstream.T3 responsible for regulating the uptake of various nutrients into cells in human body,and effectively become utilized for the production and consumption of energy.
It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.T3 increases the basal metabolic rate and, thus, increases the body's oxygen and energy consumption. The basal metabolic rate is the minimal caloric requirement needed to sustain life in a resting individual. T3 acts on the majority of tissues within the body, with a few exceptions including the spleen and testis. It increases the production of the Na+/K+ -ATPase and, in general, increases the turnover of different endogenous macromolecules by increasing their synthesis and degradation.
Liothyronine is the most potent form of thyroid hormone. Chemically, it is nearly identical to T3. As such, it acts on the body to increase the basal metabolic rate, affect protein synthesis and increase the body's sensitivity to catecholamines by permissiveness.
The thyroid hormones are essential to proper development and differentiation of all cells of the human body. These hormones also regulate protein, fat, and carbohydrate metabolism, affecting how human cells use energetic compounds.It usually used as treatment of depressive disorders and as a fat loss supplement.
Item | Specification | Result | |
Appearance | An odorless, almost white or buff colored powder | pass | |
Solubility | 1,Very slightly soluble in water | pass | |
2,slightly soluble in alcohol | pass | ||
3,practically insoluble in most other organic solvents | pass | ||
4,disolves in diluted aqueous sodium hydroxide solutions | Pass | ||
Identification | a) Heat about 50 mg with a few drops of sulfuric acid in a porcelain crucible: violet vapors of iodine are evolved. | pass | |
b)The retention time of the major peak is confirm to the RS | pass | ||
Loss on Drying | Not more than 4.0% | 0.46% | |
[a]20/D C=1 in 1M HCl/EtOH 1:4 |
+18 ~ +22o | +20.9o | |
Assay(HPLC) | Not less than 95.0% | 99.18% | |
Levothyroxine sodium | Not more than 5.0% | 0.68% | |
Conclusion: | Up to the Standard for Export |
T3 does speed fat loss. As a guideline, for most 12.5 mcg/day is a conservative "supplement" sort of dosing that seems to have no detectable adverse effect on thyroid function at all. 25 mcg/day is a "supplement" sort of dosing that does have some inhibitory effect. 50 mcg/day is a reasonably conservative bb'ing sort of dose that, of course, is more inhibitory. 75 mcg/day is getting into more of a problem area; 100 mcg/day in many cases leads to loss of muscle size and strength.
These doses are in reference to legit T3 provided in tablets such as Cytomel. Liquid formulations are usually unstable and as a result, the above numbers in many cases won't match up to experiences with liquid products, or for that matter, experience with a liquid product at one time may not match up with experience at a different time, due to the stability problem. Individuals do vary in this but 100 mcg/day is very often quite weakening and muscle-catabolic. So far as wanting more rapid fat loss than what is achieved with 50 mcg/day, personally I'd look elsewhere than adding more T3.
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